Selected Publications
1.
A Oken, J Lee, S David, Q Xie, C Dennison and JZ Chen (2019). "Z-contrast
enhancement enables cryo-EM structure determination of a 47 kDa
protein." Submitted.
2.
JZ Chen (2019).
"#Protein lights up in cryo-EM." Microscopy and Microanalysis 25 (S2): 1222-1223.
DOI:10.1017/S1431927619006846.
3.
WC Thomas, FP Brooks, AA Burnim,
JP Bacik, J Stubbe, JT Kaelber, JZ Chen and N Ando (2019). "Convergent allostery
in ribonucleotide reductase."
Nature Communications 10(1): 2653.
4.
JZ Chen
(2018). "Single-Particle 3D Reconstruction beyond the Nyquist Frequency." Proceedings of IEEE International
Conference on Bioinformatics and Biomedicine, 2018: 2442-2445.
5.
BL Brown, EF Vieux, T Kalastavadi, S Kim, JZ Chen and TA Baker (2018). "N domain of the Lon AAA+ protease controls
assembly and substrate choice." Protein Science, PMID: 30461098.
6.
JF Fay, LA Aleksandrov, TJ
Jensen, LL Cui, JN Kousouros, L He, AA Alexsandrov, DS Gingerich, JR
Riordan* and JZ Chen* (2018).
"Cryo-EM Visualization of an
Active High Open Probability CFTR Anion Channel." Biochemistry 57(43): 6234-6246.
7.
P Monette, R Brach, A Cowan, R Winters, J Weisman, F Seybert, K Goguen, JZ Chen, A Glasfeld and G Spatafora
(2018). "Autoregulation of the Streptococcus mutans SloR Metalloregulator is
Constitutive and Driven by an Independent Promoter." Journal of Bacteriology 200(14). PMID: 29735764.
8.
GM Martin, C Yoshioka, EA Rex, Q Xie,
MR Whorton, JZ
Chen*, SL Shyng* (2017). "Cryo-EM structure of the ATP-sensitive
potassium channel illuminates mechanisms of assembly and gating."
eLife 2017; 6:e24149. PMID:
28092267. (*
Co-communication authors)
9.
R Marabini, B Carragher, S Chen, JZ
Chen, A Cheng, KH Downing, J Frank, RA Grassucci,
H Bernard, W Jiang, S Jonic, HY Liao, SJ Ludtke, S Patwari, AL Piotrowski,
A Quintana, CO Sorzano, H Stahlberg, J Vargas, NR
Voss, W Chiu and JM Carazo (2015).
"CTF Challenge: Result Summary." Journal of Structural Biology 190(3): 348-359.
10.
BA Sosa, FE Demircioglu, JZ
Chen, J Ingram, HL Ploegh and TU Schwartz
(2014). "How lamina-associated polypeptide 1 (LAP1) activates Torsin."
eLife 2014; 3:e03239. PMID: 25149450.
11.
D Barthelme*, JZ
Chen*, J Grabenstatter, TA Baker and RT Sauer
(2014). "Architecture and
assembly of the archaeal Cdc48*20S proteasome." PNAS 111(17): E1687-1694. (* Co-first
authors)
12.
KR Andersen, E Onischenko,
JH Tang, P Kumar, JZ Chen, A Ulrich, JT Liphardt, K Weis and
TU Schwartz (2013). "Scaffold
nucleoporins Nup188 and Nup192 share structural and functional properties with
nuclear transport receptors."
Elife 2:
e00745.
13.
EF Vieux, ML Wohlever, JZ Chen, RT Sauer and TA Baker
(2013). "Distinct
quaternary structures of the AAA+ Lon protease control substrate degradation." PNAS 110(22): E2002-2008.
14.
AF Brilot, JZ Chen, A Cheng, J Pan, SC Harrison,
CS Potter, B Carragher, R Henderson and N Grigorieff (2012).
"Beam-induced motion of vitrified specimen on holey carbon film." Journal of Structural Biology 177(3):
630637.
15.
R Henderson, S Chen, JZ Chen, N Grigorieff, LA Passmore, L Ciccarelli, JL Rubinstein, RA Crowther, PL Stewart, PB
Rosenthal (2011). "Tilt-Pair
Analysis of Images from a Range of Different Specimens in Single-Particle
Electron Cryomicroscopy." Journal of Molecular Biology 413(5):
1028-1046.
16.
EC Settembre*, JZ Chen*, PR Dormitzer,
N Grigorieff and SC Harrison (2011). "Atomic
model of an infectious rotavirus particle." EMBO J. 30(2): 408-416. (* Co-first
authors)
17.
JZ Chen*, EC Settembre*, ST Aoki, X Zhang, AR Bellamy, PR Dormitzer, SC Harrison and N Grigorieff
(2009). "Molecular interactions in rotavirus assembly and uncoating seen by high-resolution cryo-EM." PNAS 106(26): 10644-10648. (* Co-first authors)
18.
JZ Chen, C Sachse, C Xu, T Mielke, C Spahn and N Grigorieff (2008).
"A Dose-Rate Effect in Single-Particle Electron Microscopy." Journal of Structural Biology 161(1): 92-100.
19.
C Sachse, JZ Chen, P Coureux,
ME Stroupe, M Fandrich and
N Grigorieff (2007). "High-Resolution Electron
Microscopy of Helical Specimens: A Fresh Look at Tobacco Mosaic Virus." Journal of Molecular Biology 317(3): 812-835.
20.
JZ Chen and N Grigorieff (2006). "SIGNATURE: A single-particle
selection system for molecular electron microscopy." Journal of Structural
Biology 157(1): 168-173.
21.
TR Shaikh, DR Thomas, JZ Chen, FA Samatey, H Matsunami, K Imada, K Namba and DJ DeRosier (2004).
"A Partial Atomic Structure for the Flagellar Hook of Salmonella
Typhimurium." PNAS 102(4): 1023-1028.
22.
FA Samatey, H Matsunami, K Imada, S Nagashima, TR Shaikh, DR Thomas, JZ Chen, DJ DeRosier, A Kitao and K Namba (2004). "Structure of the Bacterial Flagellar
Hook and Implication for the Molecular Universal Joint Mechanism."
Nature 431: 1062-1068.
23.
JZ Chen, J Furst, MS Chapman and N Grigorieff
(2003). "Low-Resolution Structure Refinement in Electron Microscopy."
Journal of Structural Biology 144: 144-151.
24.
J Furst, RB Sutton, JZ Chen, AT Brunger
and N Grigorieff (2003). "Electron Cryomicroscopy Structure of N-Ethyl Maleimide
Sensitive Factor at 11 Resolution." The EMBO Journal 22(17):
4365-4374.
25.
SM Pizer, PT Fletcher, S
Joshi, A Thall, JZ Chen, Y Fridman, DS Fritsch, AG Gash,
JM Glotzer, MR Jiroutek, CL
Lu, KE Muller, G Tracton, P Yushkevich
and EL Chaney (2003). "Deformable M-reps for 3D Medical Image
Segmentation." International Journal of Computer Vision 55: 85-106.
26.
JZ Chen, SM Pizer, EL Chaney and S Joshi (2002). "Medical Image
Synthesis via Monte Carlo Simulation." Medical Image Computing and
Computer Assisted Intervention 2488:
347-354.
27.
SM Pizer, S Joshi, T
Fletcher, M Styner, G Tracton
and JZ Chen (2001). "Segmentation
of Single-Figure Objects by Deformable M-reps." Medical Image
Computing and Computer Assisted Intervention 2208: 862-869.
28.
JZ Chen and MS
Chapman (2001). "Conformational
Disorder of Proteins Assessed by Real Space Molecular Dynamics Refinement."
Biophysical Journal 80: 1466-1472.
29.
JZ Chen, E Blanc
and MS Chapman (1999). "Real Space
Molecular Dynamics Structural Refinement." Acta
Crystallographica D55: 464-468.
30.
JZ Chen, E Blanc
and MS Chapman (1999). "Improved
Free R-factors for the Cross Validation of Macromolecular Structures."
Acta Crystallographica D55: 219-224.